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Metrohm AG is a leading provider of instruments and know-how for chemical analysis in the lab and in the process, specializing in titration, ion chromatography, electrochemistry, and spectroscopy.

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$0~$10(22)
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$100~$200(852)
$200~$300(610)
$300~$400(376)
$400~$500(277)
$500~$750(602)
$750~$1000(560)
$1000~$5000(1323)
$5000~$10000(63)
$10000~$50000(135)
$50000~$100000(9)
$100000~$3000000(10)

Additional Information

Vapor Pressure: 0.55mbar at 20°C

Additives

Without: Calcium, magnesium, phenol red

Without: Calcium, magnesium

Application

For method scouting, group separations, sample concentration and sample clean-up of charged biomolecules

Cell isolation

For the purification of GST-tagged proteins from bacterial lysates and other glutathione S-tranferases or glutathione-dependent proteins and for preparation of cytoplasmic extract

Application_4

Cell isolation

Chromatography system|Manual

Applications

thin layer chromatography (TLC): suitable

gas chromatography (GC): suitable

HPLC: suitable

Base Style

Flat Bottom

Bed Height

100 mm

600 mm

25 mm

Bed Support

Filter

Net

Autoclavable

Not Autoclavable

Autoclavable

Autoignition Temp

800 °F

Bed Dimensions

16 x 25 mm

7 x 25 mm

Bed Volume

5 mL

1 mL

Assay

=99%

Carton Qty

1000

200

BioProcess resin

yes

Boiling Point

189°C

2230 C

CAS Registry Number 1

631-61-8

67-68-5

7631-86-9

Brand

PYREX®

CAP COLOR

Blue

Green

Cap Material

HDPE

LDPE

Capacity

1.3 meq/mL by wetted bed volume

1.7 meq/mL by wetted bed volume

4.7 meq/g by dry weight

2.4 mL

CarbonLoad

11%

15%

CAS_NO

112926-00-8

1343-88-0

67-56-1

7631-86-9

9003-70-7

9004-34-6

9052-95-3

39389-20-3

69011-20-7

7440-44-0

69011-19-4

ChEBI

CHEBI:28262

CHEBI:62947

Chem AlertStorageSymbol

Gray

Chemical Name or Material

Ammonium Acetate

Dimethylsulfoxide

Silica Gel

Certificate of Analysis

Yes

Certifications/Compliance

Manufactured in cGMP (21 CFR 820) compliant and ISO9001 certified facilities

Chem Alert Storage Symbol

Gray

Aluminum Al

20 ppb max.

Chemical Stability

Resistant to aqueous solutions and solvents used in liquid chromatography. Not resistant to Acetone, Ketones, Chlorinated Hydrocarbons, Aliphatic Esters and Phenol. Should be avoided: >10% NaOH, >10% HCl, >5% acetic acid, and strong mineral acids.

Stable in aqueous buffers commonly used in protein A chromatography, 8 M urea, 6 M gua-HCl, 2% benzyl alcohol, 10 mM NaOH (pH 11), 0.1 M sodium citrate/HCl (pH 3), 20% ethanol

Commonly used aqueous buffers

Stable to commonly used aqueous buffers:1.0 M NaOH, 8 M urea, 8 M guanidine hydrochloride, 70% ethanol

Resistant to most solutions used in liquid chromatography except Hydrocarbons, Aromatic solvents and Chlorinated Hydrocarbons

The columns are designed to be used in aqueous solutions and most organic solvents commonly used in liquid chromatography of biomolecules, with the following few exceptions: chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol

Chemical Substance ID

24870506

24852837

329759181

329763461

24857358

329750331

329759187

329763462

Chemical Stability (Column Hardware)

Resistant to most solutions used in liquid chromatography except hydrocarbons, aromatic solvents, and chlorinated hydrocarbons.

Chromatography technique

Hydrophobic Interaction Chromatography

Histidine-tagged protein purification

Ion Exchange Chromatography

Antibody affinity chromatography

Group specific affinity

GST-tagged protein purification

Closure Color

Clear

Black

Silver

Blue

Closure Material

Aluminum

Polyethylene

Glass

Polypropylene

Plastic

Closure Size

8 mm

13-425

8-425

13 mm

20 mm

9 mm

Closure Type

Crimp Cap

Screw Cap

Plug

With Titeseal Open-bottom Plug Style Plastic Closures, Unattached

ClosureType

Screw Cap

Crimp Cap

Screw thread

Screw Top

Snap Cap

Crimp Top

Open-Top Screw

Color

Gold/Brown

Amber

Colorless to Slightly Yellow

N/A

Gold

Graphite

Silver/Gray

COLOR

Green

Natural

Orange

Red

Black

Clear

White

Yellow

Blue

Color

Tan

red band

colorless

Grey

Blue/Tan

Brass

Multi

Silver

Column Feature

Fritted disc

Reservoir

Column Format

Analytical Column

Analytical Column, EASY-Spray

Column i.d.

10 mm

16 mm

26 mm

5 mm

50 mm

Column Phase

ENVI-Carb

Column Type

capillary polar

Empty Column, Polyethylene Filter

SPE

capillary extremely polar

Reversed Phase

capillary chiral

capillary non-polar

Mixed Mode

packed GC

Size-Exclusion, Proprietary Resin

Compatibility

Compatible with most QuEChERS shakers.

Composition

bed wt., 100 mg

bed wt., 500 mg

magnesium sulfate, 150 mg

magnesium sulfate, 6 g

Discovery ® DSC-18, 400 mg

Tris Base, Sodium Chloride

Concentration

20 X

Chemical/Physical Resistance

Temp. Limits:. -10 C to 180 C isothermal and programmed

Swelling (dry to solvent saturated, %):hexane 10-15; toluene 10-15; ethylene dichloride 15-20; ethylene acetate 30-40; 95% ethylene alcohol 60-70; water 60-70.

ClosureMaterial

Aluminum

Polypropylene

Connections

1/8 in. Compression

Content AndStorage

Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, between the following temperatures: 20 to 25°C.

Upon receipt store at 4°C.

Copper Cu

10 ppb max.

ClosureSize

9 mm

Column Capacity

< 1 mg/mL

Column Color

Natural

Column Material

Polystyrene (PS)

Polypropylene (PP)

Column volume

8 mL

Density

1.100g/cmÂ³

0.12 µm

0.20 µm

Density Max.

1.2 g/ml

Diameter English Outer

0.3 in.

0.355 in.

0.305 in.

Diameter English Outer Needle

0.028 in.

0.0283 in.

Diameter Metric Inner

6.6 mm

12 mm

Diameter Metric Inner Needle

0.41 mm

Description

For gas: Inert carrier, He, H2, N2, AR, Air

1/16 in., 0.37 in. Head

Diameter Metric Outer

12 mm

15 mm

7.75 mm

8 mm

Connection Type

Cemented

Fixed

CutOfforExclusionLimit

7.0 kDa

Diameter Metric

75 µm

2.1 mm

EC Number

215-691-6

231-545-4

231-153-3

215-609-9

215-681-1

232-674-9

Feature

preconditioned

Endcapped

syringe type Sample Lock

closure type screw top vial

Fluorescent Indicator

Not Endcapped

Reusable

luer lock without slots

needle type N (cemented)

Features and Benefits 4:

Minimized risk – The robust design of the system greatly reduces the chances of contamination and user errors, minimizing troubleshooting and downtime

Features and Benefits 5:

Controlled assembly – Precise control over fluid flow rates and ratios allows fine-tuning of the critical quality attributes (CQAs), including particle size, to your specifications

Reproducible: NxGen™ technology ensures consistent, controlled mixing conditions, enabling reproducible, robust particle formation.

Features and Benefits 6:

Scalable – The system enables modeling of clinically relevant parameters and processes at small volumes to predictably scale optimized formulations on the NanoAssemblr™ Blaze system and NanoAssemblr™ commercial formulation system

Flow Rate

< 20 ml/min|< 20 ml/min

< 4 mL/min

< 4 ml/min|< 4 ml/min

< 20 mL/min

< DarcyÂ´s Law

2 ml/min - 10 ml/min

Recommended: 0.5 to 2.0 mL/min

Flow Velocity

< 450 cm/h

< 150 cm/h

15 cm/h

< 300 cm/h|< 300 cm/h

< 60 cm/hour

<1800 cm/h

15 cm/h|15 cm/h

For Use With Application

Chromatography

Ideal for manual and automated HPLC injections, commonly used in syringe pumps and other liquid handling instruments

Food and Beverages

GC/LC

TLC

Diameter Metric Outer Needle

0.72 mm

Estimated Shelf Life from Manufacture Date

5 years

Format

matrix material

Format_6

Prepacked columns

Prepacked column

Bulk resin

Form

Liquid

Form

neat

powder or crystals

fine powder

powder

Formula Weight

60.08

Format

Liquid

Endcapped

Yes

Features and Benefits 1:

Accelerated timelines – Simplified workflows and comprehensive technical support expedite drug development and data generation

Efficient: Validate end-to-end clinical manufacturing processes, including tangential flow filtration (TFF), sterile filtration, and fill/finish operations on a preclinical system with a simplified setup and shorter run times, saving time and resources.

Features and Benefits 3:

Easy to use – Simple workflows and intuitive software allow users to be up and running quickly

Closed system environment: The Blaze+ system provides a closed system environment that enables external vessel connections and includes a software upgrade, reducing the risk of contamination during scale-up.

Application_5

Chromatography system|Manual

Formula

MgO₃Si

Service & Support

CH₃OH

O2Si

For use with_31

AKTA go protein purification system

Grade

High-Purity Grade

HPLC

analytical standard

for GC derivatization

Standard

Grade

Technical Grade

H-Codes

H351

H315-H319-H335

H317

H319

H372

Height Metric

32 mm

Bed Height With Two Adaptors

0 to 200 mm

Harmonized Code EU

39269097

Height English

1.77 in.

18 in.

Height Metric

45 mm

Hold-up Volume of Membrane

<10 Î¼l

Identification

Pass Test

Includes

Instructions supplied with the concentractors

Connectors for high- and low-pressure chromatography equipment and instructions.

Dismantling tool, support screen, net ring (10 Î¼m), O-ring, stop plugs, and instructions.

Inlet id

0.75 mm (0.029 in)

1 mm (0.04 in)

IOD-Codes

Ion Exchanger Type

Strong anion exchanger

Weak cation exchanger

Strong cation exchanger

Weak anion exchanger

Bore Size (mm)

Business Unit

Length English

2 in.

Licensing

For licensing information, see the Licensing Statements page in the About Us section.

Ligand

Cibacron Blue

Glutathione and 10-carbon linker arm

Phenyl

Quaternary amine

Carboxymethyl

Sulphopropyl

Alkali-stabilized Protein A-derived (E. coli)

Diethylaminoethyl

Glutathione

Recombinant protein G lacking albumin-binding region, produced in E. coli

Recombinant GammaBind G type 3 lacking albumin-binding region

TALONÂ® Superflow Cobalt-IMAC

Ligand Coupling Method

Cyanogen bromide activation

Epoxy activation

Maleimide activation

Ether linkages

InChIKey

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Linear Formula

(C10H12 · C10H10 · C8H8)x

(CH₃)₂SO

CH3COONH4

MgO3Si

MarkingSpot

Yes

Material

Aluminum

Borosilicate glass

Borosilicate Glass (Type 1)

Glass Support

Metal

Polypropylene

Polypropylene (PP)

Steel

Vespel/Graphite

black polypropylene cap

clear glass vial

glass TD tube

Polycarbonate (PC)

PTFE/silicone septum

SilTite

Tedlar ® PVDF film

Vespel/Graphite, VG1

Alumina

aluminum support

bevel tip stainless steel needle (point style 2)

blue polypropylene cap

Cellulose

Fused Silica

Glass Body

Graphite

N/A

PE frit (20 µm porosity)

PTFE Luer lock

Silica gel

Silicone

Stainless steel

Vespel

VG2, 60% Vespel/40% Graphite

Brass

multiple

PEEK

Plastic/Stainless Steel

polypropylene hardware

PTFE

VG1, 85% Vespel/15% Graphite

Material

Borosilicate Glass, PTFE, Polyethylene, FKM/FPM

PTFE Frit

Stainless Steel Column

Steel/Plastic

Mixed

Polypropylene Tube

Material Barrel

Borosilicate Glass

Material Plunger

Stainless Steel

Matrix

cross-linked agarose, 4%, spherical

Cross-linked agarose, 6%

Highly cross-linked agarose, 6%

Highly crossed-linked agarose, 6%

Composite of cross-linked agarose and dextran

cross-linked, 6% agarose particles

Highly cross-linked agarose

cross-linked agarose, 6%, spherical

Cross-linked dextran

Composite of cross-linked agarose

Highly cross-linked agarose with dextran surface extender

Highly cross-linked agarose, spherical

Hydroxypropylated, cross-linked dextran

Max Temperature Metric

50°C

Maximum pressure over packed bed

4.0 MPa (40 bar, 580 psi)

Includes

Two (0.5 m and 2 m L) 1/16 in. OD PTFE tubing assembly with 1/4-28 UNF PP fitting at one end, a frit kit (contains two each of 10 µm PE, 10 µm PTFE, and 30 µm PTFE frits), and a Click-N-Seal 10-32 PEEK conical port fitting.

Vials and Closures

MDL Number

MFCD00011232

MFCD00132722

MFCD00133992

MFCD00078249

MFCD00081512

MFCD00145841

MFCD00146442

MFCD00004595

MFCD00132707

MFCD00132718

MFCD00132726

Ionic Capacity

0.18-0.25 mmol H⁺/ml medium

0.09-0.13 mmol H⁺/ml medium

0.11â€“0.16 mmol (Cl^-)/mL resin

0.18-0.24 mmol Cl^-/ml medium

IUPAC Name

azanium;acetate

methylsulfinylmethane

Jar Style

Chromatography tank

Melting Point

18.4°C

114°C

Length (mm)

38.3

Length English Needle

2 in.

Length Metric

150 mm

60 m

50 mm

51 mm

Length Metric

250 mm

100 mm

Ligand

Recombinant Protein A (E.coli)

Ligand_7

Protein L

Protein A

Protein A, alkali stabilized

Protein G

Liner Material

PTFE/Silicone

PTFE/Rubber

Iron Fe

10 ppb max.

Magnesium Mg

10 ppb max.

Marking Spot

Matrix

Highly cross-linked 4% agarose

6% Cross-Linked Agarose

Max Pressure

11600 psi (800 bar)

1000 psi

14500 psi (1000 bar)

200 psi

4500 psi (310 bar)

17400 psi (1200 bar)

2000 psi

900 psi

Max Temperature English

122°F

239°F

Molecular Formula

C2H7NO2

C2H6OS

O2Si

Molecular Weight

32.04

60.08

0.0

100.39

77.083

12.01

78.129

Ligand Concentration

~45 Âµmol phenyl/mL resin

Ligand Density

6 mg rProtein A/ml medium

2 mg Protein G/ml medium

3 mg GammaBind G, type 3/ml medium

Manganese Mn

10 ppb max.

MATERIAL

Glass

LDPE

Material Tip

PTFE

Max Temperature

40°C

Min Temperature Metric

10°C

MinTemperature English

50°F

Multi-Step Purification

Yes, (optional)

Needle Point Style

Tapered

Blunt

Sharp, Bevel, Curved, Non-coring

Needle PointNumber

Nitrate

0.001% max.

Operating Flow Rate, Max

1.0 mL/min

2.6 mL/min

0.15 mL/min, water at room temperature;
0.075 mL/min, 20% ethanol or 10% glycerol at room temperature;
0.075 mL/min water at low temperature;
0.035 mL/min 20% ethanol or 10% glycerol at low temperature

Operating Flow Rate, Recommended

0.5 mL/min

0.075 mL/min

1.3 mL/min

Operating pH

0 - 14

2 - 8

3.8 - 6.8

1 - 9

2 - 7.5

2 - 9

3.5 - 7.0

Optical Activity

~7 (5% in H 2 O, suspension)

7.0 (5% in slurry)

6.5 (5% in slurry)

Order Information

Percoll is for research use only.

Tricorn have Valco fittings for AKTAdesign systems and are supplied with M6 connectors for FPLC System. Tricorn columns are design patented, RESOURCE columns are supplied with connectors for high- and low-pressure chromatography equipment and instructions

Use 20-40 mM imidazole in sample and binding buffers for highest purity.

Percoll PLUS is for research use only.

This product is produced based on a customer order. Delivery time may be longer than for standard products.

Tricorn have Valco fittings for AKTAdesign systems and are supplied with M6 connectors for FPLC System. Tricorn columns are design patented. RESOURCE columns are supplied with connectors for high- and low-pressure chromatography equipment and instruction

Outlet id

0.75 mm (0.029 in)

1.0 mm (0.04 in)

1.55 mm (0.06 in)

Outlet Pressure

10 to 100 psig

Outlet Size

1/8 in.

Overview

The NanoAssemblr™ Blaze and Blaze+ systems streamline the process development of lipid nanoparticle (LNP) formulation, enabling the efficient scaling from early research through preclinical and early clinical development. With flexible volume options and a closed system environment, these systems support early chemistry, manufacturing, and control (CMC) studies and large-scale protocol development for upstream and downstream operations, providing valuable insights into processes and consumables required for GMP manufacturing.

The NanoAssemblr™ Ignite and Ignite+ systems enable scalable, reproducible, and easy-to-use formulation of lipid nanoparticles (LNPs) for preclinical genomic medicine development.

Overview 4

Starting June 2025, customers can purchase the new NxGen™ Blaze cartridges for the NanoAssemblr™ Blaze nanoparticle formulation system and will have the option to reuse them. Blaze system NxGen™ cartridges remain validated for single use only, up to 1 L on the Blaze system or 10 L on the Blaze+ system. Further information can be found in the Blaze user guide.

Scalable NxGen™ technology NanoAssemblr™ Ignite and NanoAssemblr™ Ignite+ systems feature NxGen™ technology, an advanced mixing architecture that uses toroidal structures within the flow path to maintain steady, consistent mixing conditions. This enables effective transfer of critical process parameters (CPPs) during scaling up while maintaining reproducibility and control.

P-CODES

P280

P314

P305 + P351 + P338

Metal Ion Capacity

approx. 15 Âµmol Ni²⁺/ml medium

~15 Âµmol Ni²⁺/ml medium

Pack size

100 g

5 mL

50 mL

500 mL

1 Ã— 4.7 mL

1 Ã— 5 mL

1 mL

10 mL

150 mL

2 x 1 mL

200 mL

25 mL

250 mL

50 Ã— 100 ÂµL

50 columns

500 g

6 mL

6 x 500 mL

7 Ã— 1 mL

1 Ã— 1 mL

1 piece

100 mL

20 mL

300 mL

5 Ã— 5 mL

6 x 100 mL

75 mL

1 L

1000 mL

5 Ã— 1 mL

Packaging

Plastic Drum

Poly Bottle

1000/Bag

Amber glass

Glass Bottle

Packing Material

Spherical, Fully Porous, Ultrapure Silica

Spherical, Nanopolymer Hybrid Silica

Spherical, Solid Core, Ultrapure Silica

Partical Size Dry

18 Âµm-111 Âµm

40 Âµm-120 Âµm

50 Âµm-150 Âµm

Particle Shape

Spherical Solid Core

Spherical

Particle Size in Methanol Max

163

Particle size, d_50V

~90 Âµm

~90 Î¼m

~75 Âµm

~85 Âµm

~ 9 Âµm

~ 8.6 Âµm

~34 Âµm

~34 Î¼m

pH Stability Short Term

1â€“14

pH stability, CIP

2â€“10

2â€“13

2â€“13.7

3â€“12

3â€“14

1â€“14

2â€“14

3â€“10

2â€“14Co²⁺-stripped medium

2â€“9

pH stability, operational

2â€“10

2â€“13

4â€“12

3â€“10

2 to 12

2â€“12

3â€“12

3â€“9

2â€“9

3 to 12

3â€“13

4â€“13

4â€“9

Phase

Reversed Phase

Reversed Phase and Ion Exchange

Physical State

Liquid

liquidSuspension

Solid

Min Temperature English

50°F

Pore Size

0.7-0.85 cm 3 /g pore volume (approx.)

110 Å pore diameter

160 Å

60 Å pore size

0.8 cm 3 /g pore volume

120 Å

20 µm

60 +?

60 Å average pore size (52-73 Å)

60 Å mean pore size

60 Å medium pore diameter

70 Å pore size

90 Å

~0.8 cm 3 /g pore volume

0.7-0.9 cm 3 /g pore volume

100 Å

150 Å

200 Å

30 Å

300 Å

60 Å

90 Å mean pore size

90 Å pore size

0.75 cm 3 /g pore volume

100 Å

180 Å

PoreSize

80 Å

300 Å

Porosity

7 Î¼m

10 or 80 Âµm

20 Î¼m

10 Î¼m

Preslit

Pressure Limit

20 bar (2 MPa, 290 psi)

3550 C (lit.)

>1600 C

Needle Gauge

22s G

22 G

No per Pack

100

Outlet Port

compression fitting

Overview 3

The NanoAssemblr™ Ignite+ system builds on these features with expanded capabilities, formulating up to 60 mL at up to 200 mL/min. This flexibility supports small-scale de-risking of large-scale systems and initiates process development activities using simple, low-volume workflows.

The single-use tubing kit enables external vessel connections and a closed-system environment for the Blaze+ system.

p H

2 to 8

7.5 pH

2.5 to 7

PAC Code

1267

Pack Size

Packaging Layout

1 ft3 in fiber drum

1, 6x1, 2.5 kg in poly bottle

100, 500 g in poly bottle

25 kg in fiber drum

25, 500 g in poly bottle

1 kg in poly bottle

2.5, 5, 25 kg in fiber drum

Particle Size in Methanol Min

ParticleSize

2.6 µm

5 µm

3 µm

Percent Purity

≥99.9%

>=99%

7.0 to 7.4

7.0

pH ligand fully charged

Entire pH range

Above 6

Below 9

pH Range

5.5â€“7.5

8.5â€“9.5

8.9â€“9.9

pH Stability Cleaning-in-Place (CIP)

0 to 14

1 to 14

pH Stability Long Term

43843

Physical Form

Colloidal solution of silica coated with polyvinylpyrrolidone (PVP)

Colloidal solution of silica particles coated with silane

Spray-dried powder

Solid

Liquid

Pressure/flow characteristics

150-250 cm/h at <0.1MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20Â°C using buffers with the same viscosity as water)

250-400 cm/h at <0.1 MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20â°C using buffers with the same viscosity as water).

Pressure/flow characteristics: 150-250 cm/h at <0.1 MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20â°C using buffers with the same viscosity as water).

Pressure/Flow Specification

400-700 cm/h, 100 kPa, XK 50/30 column, bed height 15 cm

300 kPa at 600 cm/h, 1 m diameter column, 20 cm bed height

25-45 cm/h, pressure drop cm H2O/bed height=2, beh height 30 cm, 2.6 cm i.d.

300-600 cm/h, 100 kPa, XK 50/30 column, bed height 15 cm

base matrix 150-250 cm/h, 100 kPa, XK 50/60 column, bed height 25 cm

150 cm/h (at < 3 bar, 25Â°C, 10 cm bed height)

Base matrix: 250-400 cm/h, 100 kPa, XK 50/60 column, bed height 25 cm

Product Family

PYREX® Chromatography Column with Reservoir, PTFE Product Standard Stopcock

PYREX® Cylindrical Chromatography Jars

PYREX® Rectangular Chromatography Jars

PYREX® Apparatus, Extraction, Chromatographic, Coarse Fritted Disc

Nickel Ni

10 ppb max.

Potassium K

20 ppb max.

Power Consumption

300 VA

Noper Pack

100

Product Line

Zeba

HyperSep

Easy Spray

Pierce

Supelclean ENVI

Pressure

10 to 100 psig

Osmolality

< 30 mOsm/kg

Overview 2

NxGen™ cartridges and tubing kits Single-use NxGen™ cartridges reduce the risk of cross-contamination and are available with or without in-line dilution, which automates a key process and streamlines the LNP workflow. The cartridges use the same mixer as the NanoAssemblr™ Ignite+ and NanoAssemblr™ commercial formulation system, enabling the direct transfer of CPPs from bench to process development and clinical and commercial production.

The NanoAssemblr™ Ignite system formulates at the bench scale with volumes of up to 20 mL and flow rates of up to 20 mL/min.

Overview 5

All cartridges are validated for single use only. Beginning in September 2025, customers can request a software upgrade that allows optional reuse of current NxGen™ and NxGen™ 500 cartridges. For advanced applications, the new NxGen™ scale-ready cartridge (coming soon) is a gamma-irradiated version of the NxGen™ 500 cartridge, designed with GMP in mind and optimized to minimize risks in early-phase and small-scale clinical trials.

Package Type

200/Bag

Particle Size

2 µm

24-44 Âµm

45 Âµm-165 Âµm

45 Î¼m-165 Î¼m

24 Âµm-44 Âµm

40 to 60 µm

60 Âµm-165 Âµm

60 Î¼m-160 Î¼m

ProductLine

Assembled Kit

Accucore

Acclaim

Pictogram

GHS02,GHS07

GHS07

GHS08

Properties

Solution

Ficoll-Paque PREMIUM products constitute a range of sterile, ready-to-use density media containing Ficoll PM400, sodium diatrizoate and disodium calcium EDTA in water for injection (WFI). The densities and osmolalities of the different products have been

Protease

Protease free

Pub Chem CID

517165

679

Pump Type

Piston pump, metering type

PurityGrade Notes

Mobile phase for HPLC applications

Product Gross Weight Desc

Quantity

10 g

1000

100

100 g

200 pack

30/Pk.

5/Pk.

6 Pack

1000/Pk.

PurificationTarget

Buffer Exchange, Protein

Qty/CS

4 / Cs

1 / Cs

6 / Cs

Qty/Pk

1 / Pk

Quality

monodispersed

with moisture indicator free of heavy metals

LiChropur ™

with fluorescent indicator 254 nm

dry

Quantity

1 × 100

100 Pack

100/Pk.

1000/Cs.

200

50 g

Each

500 g

500g

1000 Pack

108

5 kg

500

50g

1/Pk.

10 Pack

144 Pack

500 mL

R-CODES

36/37/38

10-36/37/38

48/20

Reactivity and Stability

The reactivity and stability of Ficoll PM400 are determined by its hydroxyl groups and the glycosidic bonds in the sucrose residues. It is stable in alkaline and neutral solutions. At pH values lower than 3, it is rapidly hydrolyzed, especially at elevate

Recommended Storage

Ambient temperatures

Refractive Index

1.4770 to 1.4800 (at 25°C)

Relative Viscosity

5 Î·r at 20Â°C: 10% (w/v) 20 Î·r at 20Â°C: 20% (w/v) 60 Î·r at 20Â°C : 30% (w/v 180 Î·r at 20Â°C : 40% (w/v) 600 Î·r at 20Â°C : 50% (w/v)

Resin Type

MabSelect

Sepharose High Performance

Capto

Sepharose Fast Flow

Purity GradeNotes

Mobile phase for HPLC applications

S-Codes

26-36

Safety Certifications

2006/42/EC (MD), 2004/108/EC (EMC), 1999/5/EC (R&TTE)

Sample Loading Volume

Determined by desired degree of resolution [Adsorption Mode], ~2% total bed volume [Molecular Sizing], ~1% total bed volume [Partition Mode]

Sample Volume

<= 1.5 ml

<= 13 ml

4 to 50 ÂµL

600 Âµl

<= 15 ml

<= 5 ml

< 0.5 mL

Septum

None

PTFE/Silicone

Red PTFE/White Silicone

Signal Word

Warning

Danger

Silver Ag

10 ppb max.

SMILES

CC(=O)[O-].[NH4+]

CS(=O)C

Radioactive

Recommended Flow Rate

1 ml/min

Recommended maximum operational flow velocity

300 cm/h

Residueafter Evaporation

5ppm max.

Stability

Ficoll-Paque PREMIUM products are provided as sterile solutions which are stable for at least 3 yr when stored between 4Â°C and 30Â°C and protected from light. Deterioration of Ficoll-Paque PREMIUM products is indicated by the appearance of a yellow color

Percoll is provided as solution which is stable for at least 5 yr when stored between 4Â°C and 30Â°C

Percoll PLUS is provided as solution which is stable for at least 5 yr when stored between 4Â°C and 30Â°C

Stable in alkaline and neutral solutions, but are rapidly hydrolyzed in solution at pH 3, especially at elevated temperature

Stationary Phase

C18

Proprietary

Reversed Phase/Anion Exchange/Cation Exchange

Storage

-20C

15Â° to 30Â° C

2 to 8Â°C, 20% Ethanol

2 to 8Â°C, 20% Ethanol (alternative storage solution 2% benzyl alcohol)

2 C -8 C

4 to 30Â°C, 20% Ethanol + 0.2 M Sodium Acetate

4Â°C to 30Â°C, 20% ethanol

2 to 8Â°C, 0.05 M Sodium Acetate, pH 4.0 in 20% Ethanol

4 to 30Â°C

4 to 30Â°C, 0.2 M sodium acetate in 20% Ethanol

4 to 30Â°C, 20% Ethanol

4 to 8Â°C, 20% Ethanol

2-8C

4 to 30Â°C, 0.15% Kathon CG/ICP Biocide

4 to 30Â°C, dry resins. Used resins 4 to 8 Â°C in 20% Ethanol or 0.01 M NaOH

4Â°C to 8Â°C

Residue After Evaporation

5ppm max.

Scale

Lab|Process development

Lab

Lab|Process

Lab|Process development|Process

RIDADR

NONH for all modes of transport

UN 1993C 3 / PGIII

UN 3286 8(6.1)(3) / PGII

Style

Fine Filter (15-45 microns)

Coarse Filter (90-135 microns)

Medium Filter (45-90 microns)

Surface Area

250-350 m 2 /g

530 m 2 /g

550 m 2 /g

300 m²/g

=480 m 2 /g (approx.)

200 m 2 /g

300 m 2 /g

320 m 2 /g

430-530 m 2 /g

470-530 m 2 /g

475 m 2 /g

80 m 2 /g

130 m²/g

450 m 2 /g

450 m²/g

~500 m 2 /g

170 m 2 /g

100 m²/g

100 m 2 /g

289 m 2 /g

450 m 2 /g

480 m 2 /g

500 m 2 /g

500 m 2 /g (approx.)

Swelling factor

~1.7

Shelf Life

24 months

Solubility

It is delivered as a spray-dried powder and is therefore readily soluble in aqueous media when it is added slowly with concomitant stirring. Any lumps formed during this procedure will dissolve fairly quickly. Concentrations up to 50% (w/v) can easily be

Sterilization

0.1 Âµm sterile filtered

Storage Conditions

4ËšC to 30ËšC, 20% ethanol

4 - 30Â°C

4â€“30Â°C

Synonyms

QuEChERS; QuEChERS

Tedlar(R) Gas Sampling Bag

Activated magnesium silicate; Magnesium silicate

QuEChERS

Silica gel

TLC cards Silica gel

Charcoal activated

System

Sepax C-Pro|Sefia|Sepax 2

Stokes Radius

~ 10

Stopcock Style

Straight bore PTFE

Storage Temperature

Room temperature

Suitability

Autosampler compatibility:Agilent Agilent 1050/1090A Agilent 1100/1200 Agilent 7673A, 7683 Agilent 5890/7985A/6890Hitachi AS-1000, AS-2000, AS-4000 L7200/L7250LEAP Technologies CTC LC PAL, GC PAL CombiPAL HTC PAL/HTS PALPerkinElmer Autosystem/AS-2000/XL

Surface Area Metric

100 m2/g

Theoretical Plates

5000 m-1

> 38 000 m^-1

> 48 000 m^-1

Synonym

DMSO

Target Organs

Respiratory system

Type

Analytical Column

Ferrule

SPE Column

Liquid Chromatography (LC)

Low Coring Silicone

Autosampler Syringe

Microliter Syringe

Solid Phase Extraction Cartridge

Gastight Syringe

HPLC Column

Termination

Cemented Needle (N)

Luer-tip

USP Type

Vapor Density

>1 (vs air)

<1 (vs air)

Viscosity

1.98 mPa/s at 25Â°C

Volume

12 mL

10 mL

2 mL

25 mL

50 µL

1 mL

0.5 ml

2-6 ml

22 mL

250 µL

3 mL

50 mL

6 mL

Volume Metric

10 µL

100 µL

2 mL

4 mL

6 mL

Volume Metric

2.0 mL

250 µL

1 mL

Water

0.04% max.

Weight

Up to 53

Width English

13.5 in.

Typical Pressure Drop Over the Packed Bed

~ 2 MPa

~ 3 MPa

U SPType

UNSPSC Code

41131501

Thickness Metric

1.3 mm

Thread Size

10-425

20 mm

9 mm

11 mm

8-425

Vapor Pressure

0.55mbar at 20Â°C

17 mmHg ( 20 °C)

<0.1 mmHg ( 20 °C)

Total binding capacity

~50 mg hIgG/mL resin

Voltage

100 to 120/220 to 240 VAC

90-264 Universal Power Supply

Volume English

1 dr.

Wetted Part

yes

WGK

nwg

Width

215

535

Width Metric

34.2 cm

Warranty Spec

12 months on system, 24 months on PEM cell

Wetted materials1

Polyetheretherketone (PEEK)/Polytetrafluoroethylene (PTFE)

Zinc Zn

20 ppb max.

Decomposition Information

>190°C

Diameter (mm)

Disclaimer

For research use only. Not for use in diagnostic procedures.

Exclusion Limit Small Organics

5 x 10Â³

Export control classification number

EAR99

Features and Benefits 2:

Reproducible – Automated and advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogenous particles

Field14

50Â°-65Â°

Filtrate Vessel Material

Polycarbonate (PC)

Finish

Plain top

For Use With

ELSD, UV Detector

For Use With Equipment

LC Tubing

Thermo Scientific HyperSep-96 System

Trace and Focus GC Instruments

Formula Weight

77.08

Harmonized Code US

3926909910

Health Hazard 3

Emergency Overview
Combustible liquid. DMSO readily penetrates skin and may carry other dissolved chemicals into the body. Hygroscopic. Use personal protective equipment. Keep away from open flames, hot surfaces and sources of ignition. Ensure

Height

457 mm (approx.)

Height English

1.25 in.

Item Class Description

Consumables

L CMSGradientSuitability

Pass Test

Lead Pb

10 ppb max.

Material Septa

PTFE/Silicone

Silicone/PTFE

Max Temperature Metric

115°C

Multiple Sample Injection

Upgradeable to 5 samples

No per Pack

100

Osmolality

< 25 mOsm/kg

pH Monitoring

0 to 14 (optional)

Preslit

Yes

Protection Class

IP 21

Purity

>=99%

Relative Humidity

20% to 95% (noncondensing)

RTECS Number

FJ5691460

VV7315000

Shape

Round

Shipping Condition

Shipped Ambient

Sodium Na

50 ppb max.

Solubility Information

Solubility aq. soln.: insoluble.

Temperature

60°C

Titratable Acid

0.001mEq/g max.

Top Style

Ground

TSCA

Yes

UNSPSC

41131501

Viscosity Max

Volume_28

2-6 ml

Wetted Materials

Polyetheretherketone (PEEK)/Polytetrafluoroethylene (PTFE)

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