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Metrohm AG is a leading provider of instruments and know-how for chemical analysis in the lab and in the process, specializing in titration, ion chromatography, electrochemistry, and spectroscopy.

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$0~$10(25)
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$100~$200(887)
$200~$300(632)
$300~$400(384)
$400~$500(302)
$500~$750(582)
$750~$1000(569)
$1000~$5000(1332)
$5000~$10000(67)
$10000~$50000(119)
$50000~$100000(8)
$100000~$3000000(9)

Additional Information

Vapor Pressure: 0.55mbar at 20°C

Additives

Without: Calcium, magnesium

Analysis Time

20 to 200 min.

Analyte

Drugs|PAH|SVOC

Application

Cell isolation

For the purification of GST-tagged proteins from bacterial lysates and other glutathione S-tranferases or glutathione-dependent proteins and for preparation of cytoplasmic extract

For method scouting, group separations, sample concentration and sample clean-up of charged biomolecules

Application_5

Chromatography system|Manual

Application_4

Cell isolation

Chromatography system|Manual

Applications

thin layer chromatography (TLC): suitable

gas chromatography (GC): suitable

HPLC: suitable

HPTLC: suitable

solid phase extraction (SPE): suitable

Base Style

Flat Bottom

Bed Height

100 mm

25 mm

600 mm

Bed Support

Filter

Net

Autoclavable

Not Autoclavable

Autoclavable

Autoignition Temp

800 °F

842 °F

Bed Dimensions

16 x 25 mm

16 x 100 mm

16 x 600 mm

7 x 25 mm

Bed Volume

5 mL

1 mL

320

Capacity

=25 % absorption capacity (water)

1.1 meq/mL by wetted bed volume

1.2 meq/mL by wetted bed volume

0.6 meq/mL by wetted bed volume

1.7 meq/mL by wetted bed volume

4.7 meq/g by dry weight

2.4 mL

1.3 meq/mL by wetted bed volume

Capacity

250 mL

Average sample loading capacity

400 mg

Bed Height With Two Adaptors

0 to 200 mm

BedWeight

500 mg

Assay

=99%

CarbonLoad

15%

11%

Carton Qty

1000

200

Assay Percent Notes

99% min

Calcium Ca

50 ppb max.

Beilstein Registry Number

1098229

Boiling Point

2230 C

189°C

CAS Registry Number 1

631-61-8

67-68-5

7631-86-9

Binding Capacity/Column

Approx. 40 mg histidine-tagged protein/ml medium

Bore Size (mm)

Business Unit

CAP COLOR

Green

Blue

Cap Material

LDPE

HDPE

BioProcess resin

yes

Brand

PYREX®

CAS_NO

112926-00-8

1343-88-0

67-56-1

7631-86-9

9003-70-7

9004-34-6

9052-95-3

39389-20-3

69011-20-7

Chem AlertStorageSymbol

Gray

Certificate of Analysis

Yes

Certifications/Compliance

Manufactured in cGMP (21 CFR 820) compliant and ISO9001 certified facilities

Chemical Stability

Resistant to aqueous solutions and solvents used in liquid chromatography. Not resistant to Acetone, Ketones, Chlorinated Hydrocarbons, Aliphatic Esters and Phenol. Should be avoided: >10% NaOH, >10% HCl, >5% acetic acid, and strong mineral acids.

Stable to commonly used aqueous buffers:1.0 M NaOH, 8 M urea, 8 M guanidine hydrochloride, 70% ethanol

Resistant to most solutions used in liquid chromatography except Hydrocarbons, Aromatic solvents and Chlorinated Hydrocarbons

The columns are designed to be used in aqueous solutions and most organic solvents commonly used in liquid chromatography of biomolecules, with the following few exceptions: chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol

Chemical Name or Material

Silica Gel

Chemical Substance ID

329759181

24852837

24853619

Chromatography technique

Hydrophobic Interaction Chromatography

Ion Exchange Chromatography

Histidine-tagged protein purification

Antibody affinity chromatography

Group specific affinity

GST-tagged protein purification

Chemical/Physical Resistance

Temp. Limits:. -10 C to 180 C isothermal and programmed

Swelling (dry to solvent saturated, %):hexane 10-15; toluene 10-15; ethylene dichloride 15-20; ethylene acetate 30-40; 95% ethylene alcohol 60-70; water 60-70.

Closure Material

Aluminum

Polyethylene

Glass

Polypropylene

Closure Type

Crimp Cap

Screw Cap

ClosureType

Screw Cap

Screw Top

Color

Gold/Brown

Grey

N/A

Amber

Brass

Graphite

Multi

Silver/Gray

COLOR

Green

Natural

Red

Yellow

Black

Clear

White

Blue

Color

Tan

Gold

Silver

Column Feature

Fritted disc

Column Format

Analytical Column

Column i.d.

10 mm

16 mm

26 mm

5 mm

50 mm

Column Type

capillary polar

capillary chiral

Fused Silica

capillary extremely polar

Reversed Phase

packed GC

Closure Color

Black

Silver

Blue

ClosureMaterial

Polypropylene

Aluminum

ClosureSize

9 mm

Compatibility

Compatible with most QuEChERS shakers.

Composition

bed wt., 500 mg

magnesium sulfate, 150 mg

Concentration

20 X

Column Material

Polypropylene (PP)

Polystyrene (PS)

Content AndStorage

Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, between the following temperatures: 20 to 25°C.

Closure Size

13 mm

20 mm

9 mm

Column Color

Natural

Connection Type

Cemented

Customs Stat Number

9027.90

Dangerous Goods Classification

ARTICLE

0.12 µm

0.20 µm

Diameter English Outer Needle

0.028 in.

0.0283 in.

Diameter Metric Inner

6.6 mm

Diameter Metric Inner Needle

0.41 mm

Diameter Metric Outer

12 mm

15 mm

8 mm

7.75 mm

Diameter Metric

2.1 mm

4.6 mm

Diameter Metric Outer Needle

0.72 mm

EC Number

215-691-6

231-545-4

215-609-9

215-681-1

231-153-3

df (film thickness)

0.25 µm

0.50 µm

Diameter Metric

75 µm

DG Category

Feature

preconditioned

closure type screw top vial

Fluorescent Indicator

Not Endcapped

Reusable

Endcapped

No Flourescent Indicator

syringe type Sample Lock

needle type N (cemented)

Features and Benefits 4:

Minimized risk – The robust design of the system greatly reduces the chances of contamination and user errors, minimizing troubleshooting and downtime

Features and Benefits 5:

Controlled assembly – Precise control over fluid flow rates and ratios allows fine-tuning of the critical quality attributes (CQAs), including particle size, to your specifications

Features and Benefits 6:

Scalable – The system enables modeling of clinically relevant parameters and processes at small volumes to predictably scale optimized formulations on the NanoAssemblr™ Blaze system and NanoAssemblr™ commercial formulation system

Flow Rate

< 20 ml/min|< 20 ml/min

< 4 mL/min

< 4 ml/min|< 4 ml/min

< 20 mL/min

< DarcyÂ´s Law

Flow Velocity

< 450 cm/h

< 150 cm/h

15 cm/h

<1800 cm/h

For Use With Application

Chromatography

Ideal for manual and automated HPLC injections, commonly used in syringe pumps and other liquid handling instruments

Food and Beverages

GC/LC

In-Process Control in Drug Synthesis, Identity and Stability Testing of Drugs, Quality Control of Pharmaceuticals, Food and Environmental Samples, Residue Analysis in Food and Environmental Samples

Format

matrix material

Format_6

Prepacked columns

Prepacked column

Bulk resin

Disclaimer

For research use only. Not for use in diagnostic procedures.

Endcapped

Yes

Excitation Wavelength

254 nm

Estimated Shelf Life from Manufacture Date

5 years

Features and Benefits 1:

Accelerated timelines – Simplified workflows and comprehensive technical support expedite drug development and data generation

Features and Benefits 3:

Easy to use – Simple workflows and intuitive software allow users to be up and running quickly

Features & Benefits

Maximize trace-level sensitivity with kits that combine the next-generation inertness of RMX columns and Topaz inlet liners to give you a truly inert sample flow path and more confidence in your analytical data. RMX columns—featuring TriMax deactivation technology—deliver maximum inertness, sensitivity, and durability for demanding applications that include active compounds, such as semivolatiles analysis. Choose from single-taper and Precision-style Topaz inlet liners, both contain wool and are thoroughly passivated, minimizing analyte breakdown in the inlet. Get the convenience of a manufacturer-specific inlet liner and our most popular RMX-5Sil MS column format (30 m, 0.25 mm ID, 0.25 µm) in one easy order.

Next-generation TriMax deactivation creates a resilient stationary phase and exceptionally neutral sample flow path, delivering the stability needed for extended calibration intervals and more reliable data. Maximum inertness improves peak shape for problematic active compound classes, achieving lower detection limits and picogram-level sensitivity for confident quantification of a wide range of analytes. Superior column performance supports method consolidation for increased productivity and scaled-down sample extraction volumes for reduced solvent use.

Formula Weight

60.08

Features and Benefits 2:

Reproducible – Automated and advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogenous particles

Filtrate Vessel Material

Polycarbonate (PC)

For use with_31

AKTA go protein purification system

Form

powder or crystals

neat

powder

Form

Liquid

Format

Liquid

Formula

O2Si

MgO₃Si

Service & Support

Grade

for column chromatography

High-Purity Grade

analytical standard

certified reference material

for GC derivatization

high-purity grade (Davisil Grade 636)

Standard

High-purity Grade (9385)

high-purity grade (Davisil Grade 643)

high-purity grade (Davisil Grade 923)

HPLC

Grade

Technical Grade

High-purity Grade (Davisil Grade 635)

High-purity Grade (Davisil Grade 646)

H-Codes

H351

H372

H226 - H315 - H319 - H335

H315-H319-H335

H317

H319

Height

210 MM

629 mm

457 mm (approx.)

300 mm (approx.)

Height English

1.57 in.

1.25 in.

18 in.

1.77 in.

Height Metric

32 mm

45.6 cm

Harmonized Code US

3926909910

Harmonized Code EU

39269097

Health Hazard 3

Emergency Overview
Combustible liquid. DMSO readily penetrates skin and may carry other dissolved chemicals into the body. Hygroscopic. Use personal protective equipment. Keep away from open flames, hot surfaces and sources of ignition. Ensure

Height Metric

30 µm

40 mm

45 mm

Height English

0.0011 in.

Hold-up Volume of Membrane

<10 Î¼l

Identification

Pass Test

InChIKey

USFZMSVCRYTOJT-UHFFFAOYSA-N

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Includes

Instructions supplied with the concentractors

Dismantling tool, support screen, net ring (10 Î¼m), O-ring, stop plugs, and instructions.

Connectors for high- and low-pressure chromatography equipment and instructions.

Includes

US, UK and EU power cord, Water drain tube, DI cartridge, User Guide

Vials and Closures

Two (0.5 m and 2 m L) 1/16 in. OD PTFE tubing assembly with 1/4-28 UNF PP fitting at one end, a frit kit (contains two each of 10 µm PE, 10 µm PTFE, and 30 µm PTFE frits), and a Click-N-Seal 10-32 PEEK conical port fitting.

Inlet id

0.75 mm (0.029 in)

1 mm (0.04 in)

1.0 mm (0.04 in)

1.55 mm (0.06 in)

Intrinsic Viscosity

~ 17

IOD-Codes

Ion Exchanger Type

Strong anion exchanger

Strong cation exchanger

Weak anion exchanger

Weak cation exchanger

Length

20 m

30 m

15 m

Length English

2 in.

Licensing

For licensing information, see the Licensing Statements page in the About Us section.

Ligand

Cibacron Blue

Glutathione and 10-carbon linker arm

Phenyl

Quaternary amine

Carboxymethyl

Sulphopropyl

Recombinant GammaBind G type 3 lacking albumin-binding region

TALONÂ® Superflow Cobalt-IMAC

Alkali-stabilized Protein A-derived (E. coli)

Diethylaminoethyl

Glutathione

Recombinant protein G lacking albumin-binding region, produced in E. coli

Ligand Coupling Method

Cyanogen bromide activation

Epoxy activation

Maleimide activation

Ether linkages

Linear Formula

MgO3Si

(C10H12 · C10H10 · C8H8)x

(CH₃)₂SO

CH3COONH4

MarkingSpot

Yes

Material

Aluminum

Borosilicate Glass

Borosilicate Glass (Type 1)

Glass Support

Metal

Polypropylene (PP)

Steel

Vespel/Graphite

black polypropylene cap

clear glass vial

glass TD tube

Polycarbonate (PC)

PTFE/silicone septum

Silica Gel 60 F254

silica gel matrix

SilTite

Tedlar ® PVDF film

Tefzel ®

Vespel/Graphite, VG1

Brass

multiple

PEEK

PEEK adapter (one-piece design)

Plastic/Stainless Steel

polypropylene hardware

PTFE

VG1, 85% Vespel/15% Graphite

(wetted material 316 stainless steel/PEEK)

Alumina

aluminum support

bevel tip stainless steel needle (point style 2)

blue polypropylene cap

Cellulose

Fused Silica

Glass Body

Graphite

N/A

PE frit (20 µm porosity)

Polyethylene

PTFE Luer lock

Silica gel

silica gel 60 matrix

Silicone

Stainless steel

VG2, 60% Vespel/40% Graphite

Material

Borosilicate Glass, PTFE, Polyethylene, FKM/FPM

Polypropylene

PTFE Frit

Stainless Steel Column

Steel/Plastic

Mixed

Polypropylene Tube

Vespel

Material Barrel

Borosilicate Glass

Material Plunger

Stainless Steel

Matrix

cross-linked agarose, 4%, spherical

Cross-linked agarose, 6%

Highly cross-linked agarose, 6%

Highly crossed-linked agarose, 6%

Composite of cross-linked agarose and dextran

cross-linked, 6% agarose particles

Highly cross-linked agarose

Composite of cross-linked agarose

Highly cross-linked agarose with dextran surface extender

Highly cross-linked agarose, spherical

Hydroxypropylated, cross-linked dextran

cross-linked agarose, 6%, spherical

Cross-linked dextran

Max Temperature Metric

50°C

Maximum pressure over packed bed

4.0 MPa (40 bar, 580 psi)

MDL Number

MFCD00011232

MFCD00132722

MFCD00133992

MFCD00004595

MFCD00132707

MFCD00132718

MFCD00132726

MFCD00145831

MFCD00078249

MFCD00081512

MFCD00145841

MFCD00146442

Inner Diameter (ID)

0.25 mm

0.32 mm

0.18 mm

Ionic Capacity

0.18-0.24 mmol Cl^-/ml medium

0.18-0.25 mmol H⁺/ml medium

0.09-0.13 mmol H⁺/ml medium

0.11â€“0.16 mmol (Cl^-)/mL resin

Iron Fe

10 ppb max.

Item Class Description

Consumables

Item Introduction Date

5:00 AM UTC 2026-01-19

IUPAC Name

azanium;acetate

methylsulfinylmethane

Melting Point

18.4°C

114°C

Jar Style

Chromatography tank

Length (mm)

38.3

Length English Needle

2 in.

Length Metric

150 mm

250 mm

60 m

Length Metric

20 cm

100 mm

50 mm

51 mm

Ligand

Recombinant Protein A (E.coli)

Ligand_7

Protein L

Protein A

Protein A, alkali stabilized

Protein G

L CMSGradientSuitability

Pass Test

Lead Pb

10 ppb max.

Modification

w/5 m Integra-Guard Column

Liner Material

PTFE/Silicone

PTFE/Rubber

Magnesium Mg

10 ppb max.

Marking Spot

Molecular Formula

C2H7NO2

O2Si

C2H6OS

Ligand Density

2 mg Protein G/ml medium

3 mg GammaBind G, type 3/ml medium

6 mg rProtein A/ml medium

Matrix

Highly cross-linked 4% agarose

6% Cross-Linked Agarose

Max Pressure

11600 psi (800 bar)

5800 psi (400 bar)

17400 psi (1200 bar)

2000 psi

900 psi

1000 psi

14500 psi (1000 bar)

200 psi

4500 psi (310 bar)

Max Temperature English

122°F

239°F

Ligand Concentration

~45 Âµmol phenyl/mL resin

Molecular Weight

32.04

60.08

0.0

12.01

100.39

78.129

77.083

Material Septa

PTFE/Silicone

Silicone/PTFE

Manganese Mn

10 ppb max.

Max Temperature Metric

115°C

MATERIAL

Glass

LDPE

Material Tip

PTFE

Max Temperature

40°C

Multi-Step Purification

Yes, (optional)

Metal Ion Capacity

~15 Âµmol Ni²⁺/ml medium

approx. 15 Âµmol Ni²⁺/ml medium

Needle Point Style

Tapered

Blunt

Sharp, Bevel, Curved, Non-coring

Needle PointNumber

Nitrate

0.001% max.

No of Samples

10.0

Min Temperature Metric

10°C

MinTemperature English

50°F

Operating Flow Rate, Max

1.0 mL/min

2.6 mL/min

0.15 mL/min, water at room temperature;
0.075 mL/min, 20% ethanol or 10% glycerol at room temperature;
0.075 mL/min water at low temperature;
0.035 mL/min 20% ethanol or 10% glycerol at low temperature

Operating Flow Rate, Recommended

0.5 mL/min

0.075 mL/min

1.3 mL/min

Operating pH

0 - 14

2 - 8

3.8 - 6.8

1 - 9

2 - 7.5

2 - 9

3.5 - 7.0

Optical Activity

~7 (5% in H 2 O, suspension)

7.0 (5% in slurry)

~6.8 (10% in aq. suspension)

6.5 (5% in slurry)

Order Information

Percoll is for research use only.

Tricorn have Valco fittings for AKTAdesign systems and are supplied with M6 connectors for FPLC System. Tricorn columns are design patented, RESOURCE columns are supplied with connectors for high- and low-pressure chromatography equipment and instructions

Use 20-40 mM imidazole in sample and binding buffers for highest purity.

Percoll PLUS is for research use only.

This product is produced based on a customer order. Delivery time may be longer than for standard products.

Tricorn have Valco fittings for AKTAdesign systems and are supplied with M6 connectors for FPLC System. Tricorn columns are design patented. RESOURCE columns are supplied with connectors for high- and low-pressure chromatography equipment and instruction

Outlet id

0.75 mm (0.029 in)

1.0 mm (0.04 in)

1.55 mm (0.06 in)

Outlet Pressure

10 to 100 psig

Outlet Size

1/8 in.

Overview

The NanoAssemblr™ Blaze and Blaze+ systems streamline the process development of lipid nanoparticle (LNP) formulation, enabling the efficient scaling from early research through preclinical and early clinical development. With flexible volume options and a closed system environment, these systems support early chemistry, manufacturing, and control (CMC) studies and large-scale protocol development for upstream and downstream operations, providing valuable insights into processes and consumables required for GMP manufacturing.

The NanoAssemblr™ Ignite and Ignite+ systems enable scalable, reproducible, and easy-to-use formulation of lipid nanoparticles (LNPs) for preclinical genomic medicine development.

Overview 4

Starting June 2025, customers can purchase the new NxGen™ Blaze cartridges for the NanoAssemblr™ Blaze nanoparticle formulation system and will have the option to reuse them. Blaze system NxGen™ cartridges remain validated for single use only, up to 1 L on the Blaze system or 10 L on the Blaze+ system. Further information can be found in the Blaze user guide.

Scalable NxGen™ technology NanoAssemblr™ Ignite and NanoAssemblr™ Ignite+ systems feature NxGen™ technology, an advanced mixing architecture that uses toroidal structures within the flow path to maintain steady, consistent mixing conditions. This enables effective transfer of critical process parameters (CPPs) during scaling up while maintaining reproducibility and control.

P-CODES

P280

P314

P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

P305 + P351 + P338

Pack size

100 g

5 mL

50 mL

500 mL

1 Ã— 4.7 mL

1 Ã— 5 mL

1 mL

10 mL

150 mL

2 x 1 mL

200 mL

25 mL

250 mL

50 Ã— 100 ÂµL

50 columns

500 g

6 mL

6 x 500 mL

7 Ã— 1 mL

1 L

1000 mL

5 Ã— 1 mL

1 Ã— 1 mL

1 piece

100 mL

20 mL

300 mL

5 Ã— 5 mL

6 x 100 mL

75 mL

Packaging

Plastic Drum

Poly Bottle

1000/bag

Amber Glass

Glass Bottle

Packing Material

Spherical, Fully Porous, Ultrapure Silica

Spherical, Nanopolymer Hybrid Silica

Spherical, Solid Core, Ultrapure Silica

Partical Size Dry

18 Âµm-111 Âµm

40 Âµm-120 Âµm

50 Âµm-150 Âµm

Particle Shape

Spherical Solid Core

Spherical

Particle Size

10 to 12 µm

24 Âµm-44 Âµm

40 to 60 µm

60 Âµm-165 Âµm

60 Î¼m-160 Î¼m

2 µm

24-44 Âµm

45 Âµm-165 Âµm

45 Î¼m-165 Î¼m

Particle Size in Methanol Max

163

Particle size, d_50V

~90 Âµm

~90 Î¼m

~75 Âµm

~85 Âµm

~ 8.6 Âµm

~34 Âµm

~34 Î¼m

~ 9 Âµm

pH Stability Short Term

1â€“14

pH stability, CIP

2â€“10

2â€“13

2â€“13.7

3â€“12

3â€“14

1â€“14

2â€“14

3â€“10

2â€“9

2â€“14Co²⁺-stripped medium

pH stability, operational

2â€“10

2â€“13

4â€“12

3â€“10

2â€“9

3 to 12

3â€“13

4â€“13

4â€“9

2 to 12

2â€“12

3â€“12

3â€“9

Phase

Reversed Phase

Reversed Phase and Ion Exchange

Min Temperature English

50°F

Physical State

Liquid

liquidSuspension

Solid

Pore Size

0.7-0.85 cm 3 /g pore volume (approx.)

110 Å pore diameter

160 Å

60 Å pore size

~0.55 mL/g pore volume

0.8 cm 3 /g pore volume

120 Å

175 Å

20 µm

60 +?

60 Å average pore size (52-73 Å)

60 Å mean pore size

60 Å medium pore diameter

70 Å pore size

90 Å

0.75 cm 3 /g pore volume

100 Å

180 Å

~0.8 cm 3 /g pore volume

0.7-0.9 cm 3 /g pore volume

100 Å

150 Å

200 Å

30 Å

300 Å

60 Å

90 Å mean pore size

90 Å pore size

PoreSize

80 Å

300 Å

Porosity

7 Î¼m

10 or 80 Âµm

20 Î¼m

10 Î¼m

Preslit

Pressure Limit

20 bar (2 MPa, 290 psi)

Pressure/flow characteristics

150-250 cm/h at <0.1MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20Â°C using buffers with the same viscosity as water)

250-400 cm/h at <0.1 MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20â°C using buffers with the same viscosity as water).

Pressure/flow characteristics: 150-250 cm/h at <0.1 MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20â°C using buffers with the same viscosity as water).

Pressure/Flow Specification

400-700 cm/h, 100 kPa, XK 50/30 column, bed height 15 cm

300 kPa at 600 cm/h, 1 m diameter column, 20 cm bed height

150 cm/h (at < 3 bar, 25Â°C, 10 cm bed height)

Base matrix: 250-400 cm/h, 100 kPa, XK 50/60 column, bed height 25 cm

25-45 cm/h, pressure drop cm H2O/bed height=2, beh height 30 cm, 2.6 cm i.d.

300-600 cm/h, 100 kPa, XK 50/30 column, bed height 15 cm

base matrix 150-250 cm/h, 100 kPa, XK 50/60 column, bed height 25 cm

3550 C (lit.)

>1600 C

Product Family

PYREX® Chromatography Column with Reservoir, PTFE Product Standard Stopcock

PYREX® Cylindrical Chromatography Jars

PYREX® Rectangular Chromatography Jars

PYREX® Apparatus, Extraction, Chromatographic, Coarse Fritted Disc

Product Line

Zeba

HyperSep

Hypersil GOLD

Supelclean ENVI

Easy Spray

Pierce

Needle Gauge

22s G

22 G

No per Pack

100

Outlet Port

compression fitting

Multiple Sample Injection

Upgradeable to 5 samples

Overview 3

The NanoAssemblr™ Ignite+ system builds on these features with expanded capabilities, formulating up to 60 mL at up to 200 mL/min. This flexibility supports small-scale de-risking of large-scale systems and initiates process development activities using simple, low-volume workflows.

The single-use tubing kit enables external vessel connections and a closed-system environment for the Blaze+ system.

p H

2 to 8

7.5 pH

2.5 to 7

ProductLine

Assembled Kit

Accucore

Acclaim

PAC Code

1267

Pack Size

Packaging Layout

1 ft3 in fiber drum

1, 6x1, 2.5 kg in poly bottle

100, 500 g in poly bottle

25 kg in fiber drum

25, 500 g in poly bottle

1 kg in poly bottle

2.5, 5, 25 kg in fiber drum

fibre case

Particle Size in Methanol Min

ParticleSize

2.6 µm

5 µm

3 µm

Percent Purity

≥99.9%

>=99%

7.0 to 7.4

7.0

pH ligand fully charged

Entire pH range

Above 6

Below 9

pH Range

5.5â€“7.5

8.5â€“9.5

8.9â€“9.9

pH Stability Cleaning-in-Place (CIP)

0 to 14

1 to 14

pH Stability Long Term

43843

No per Pack

100

Physical Form

Colloidal solution of silica coated with polyvinylpyrrolidone (PVP)

Colloidal solution of silica particles coated with silane

Spray-dried powder

Liquid

Solid

Operating Temperature

4Â°C-35Â°C

Pictogram

GHS02, GHS05

GHS07

GHS08

GHS02,GHS07

Nickel Ni

10 ppb max.

Ordering Notes

Want help with applications or product selection? Contact us!

Osmolality

< 25 mOsm/kg

Noper Pack

100

Pore Volume

0.8 mL/g

Osmolality

< 30 mOsm/kg

Potassium K

20 ppb max.

Power Consumption

300 VA

Overview 2

The NanoAssemblr™ Ignite system formulates at the bench scale with volumes of up to 20 mL and flow rates of up to 20 mL/min.

NxGen™ cartridges and tubing kits Single-use NxGen™ cartridges reduce the risk of cross-contamination and are available with or without in-line dilution, which automates a key process and streamlines the LNP workflow. The cartridges use the same mixer as the NanoAssemblr™ Ignite+ and NanoAssemblr™ commercial formulation system, enabling the direct transfer of CPPs from bench to process development and clinical and commercial production.

Pressure

10 to 100 psig

Overview 5

All cartridges are validated for single use only. Beginning in September 2025, customers can request a software upgrade that allows optional reuse of current NxGen™ and NxGen™ 500 cartridges. For advanced applications, the new NxGen™ scale-ready cartridge (coming soon) is a gamma-irradiated version of the NxGen™ 500 cartridge, designed with GMP in mind and optimized to minimize risks in early-phase and small-scale clinical trials.

PurityGrade Notes

Mobile phase for HPLC applications

Package Type

200/Bag

pH Monitoring

0 to 14 (optional)

Particle SizeDistribution

5 to 20 µm

Quantity

10 g

1000

1000/Cs.

200 pack

30/Pk.

Each

100 g

5/Pk.

6 Pack

1000/Pk.

1/Pk.

500

Preslit

Yes

Quantity

100 Pack

100/Pk.

200

1 × 100

100

50 g

500 g

500g

1000 Pack

108

10 Pack

250g

5 kg

144 Pack

50g

500 mL

Properties

Solution

Ficoll-Paque PREMIUM products constitute a range of sterile, ready-to-use density media containing Ficoll PM400, sodium diatrizoate and disodium calcium EDTA in water for injection (WFI). The densities and osmolalities of the different products have been

Protease

Protease free

R-CODES

36/37/38

10-36/37/38

48/20

Pub Chem CID

517165

679

Recommended Storage

Ambient temperatures

Product Gross Weight Desc

Refractive Index

1.4770 to 1.4800 (at 25°C)

Protection Class

IP 21

Pump Type

Piston pump, metering type

PurificationTarget

Buffer Exchange, Protein

Qty/CS

4 / Cs

1 / Cs

6 / Cs

Qty/Pk

1 / Pk

Quality

monodispersed

with moisture indicator free of heavy metals

dry

LiChropur ™

with fluorescent indicator 254 nm

Purity

>=99%

Residueafter Evaporation

5ppm max.

Reactivity and Stability

The reactivity and stability of Ficoll PM400 are determined by its hydroxyl groups and the glycosidic bonds in the sucrose residues. It is stable in alkaline and neutral solutions. At pH values lower than 3, it is rapidly hydrolyzed, especially at elevate

Scale

Lab|Process development

Lab

Lab|Process

Lab|Process development|Process

Septum

PTFE/Silicone

None

Red PTFE/White Silicone

Relative Viscosity

5 Î·r at 20Â°C: 10% (w/v) 20 Î·r at 20Â°C: 20% (w/v) 60 Î·r at 20Â°C : 30% (w/v 180 Î·r at 20Â°C : 40% (w/v) 600 Î·r at 20Â°C : 50% (w/v)

Purity GradeNotes