Used to passivate your LC system before your first analysis if you:
(a) are analyzing phosphorylated compounds or other polar molecules known to chelate or interact with metal ions in your LC (e.g., glyphosate);
and also
(b) have stainless steel in your instrument flow path;
and/or also
(c) your LC column hardware is showing activity towards phosphorylated compounds or other polar molecules known to chelate.