Tag-lite CLIP-Red Labeling Reagent, 500 nmoles

Over the past few years, SNAP-Tag, CLIP-Tag, and Halo-Tag technologies combined with TR-FRET have paved the road to the development of many non-radioactive, no-wash binding assays. The method is based on transfecting cells using plasmids encoding a SNAP-Tag (or CLIP-Tag, or Halot-Tag) and subsequently labeling them with acceptors or donors. CLIP-Red allows the labeling of CLIP-Tagged proteins with a red fluorophore.

Tag-lite assays offer many features and applications over traditional receptor/ligand binding assays:

• Non-radioactive
• Homogeneous and filtration-free
• Ready-to-use kits and reagents for binding assays
• Does not alter the receptor pharmacology
• Peer-reviewed, validated technology
• Thorough kinetic studies with true K_d and K_i values, association (K_on) and dissociation (K_off) rate constants
• Screening and profiling of biologics and large molecules