Tag-lite pSNAP-Adrenergic 1 Receptor Plasmid, 10 µg

Over past few years, SNAP-Tag technology combined with TR-FRET has paved way development of many non-radioactive, no-wash, binding assays. method is based on transfecting cells using plasmids encoding a SNAP-Tag and subsequently labeling m with Terbium. Revvity offers a large collection of such plasmids. All GPCR genes are cloned in an expression vector directly downstream from a CMV promoter, and are provided ready protein expression and labeling.

All information on this page pertains to Tag-lite plasmid cloned with Beta2 adreno receptor.

Tag-lite assays offer many features and applications over traditional receptor/ligand binding assays:

• Non-radioactive
• Homogeneous and filtration-free
• Ready-to-use kits and reagents for binding assays
• Does not alter the receptor pharmacology
• Peer-reviewed, validated technology
• Thorough kinetic studies with true K_d and K_i values, association (K_on) and dissociation (K_off) rate constants
• Screening and profiling of biologics and large molecules