NEXTFLEX Cas9-gRNA rRNA Depletion Enzyme (HMR) - 50 units

The NEXTFLEX™ Cas9-gRNA rRNA Depletion Enzyme (HMR) powered by Jumpcode® DepleteX™ technology, is a standalone, workflow-agnostic depletion enzyme that removes ribosomal RNA sequences from human, mouse, or rat libraries. You can drop it into any bulk or single cell RNA-seq workflow, increasing usable reads for informative transcripts and improving coverage across the transcriptome. NEXTFLEX Cas9-gRNA rRNA Depletion Enzyme is provided at 5.6 µM and includes 435 unique guide RNAs targeting nuclear 5S, 5.8S, 18S, 28S, 45S and mitochondrial 12S and 16S rRNA loci. It requires a simple one-hour incubation making integration straightforward in pre- or post-PCR cleanup steps depending on your workflow. Designed to be highly cost-competitive and universally compatible, it delivers robust rRNA depletion without locking you into a specific library prep kit.