High Capacity Magne(TM) Streptavidin Beads

High Capacity Magne Streptavidin Beads are magnetic affinity beads with high specificity and high capacity for binding biotinylated antibodies and proteins. The magnetic beads are composed of iron encapsulated by macroporous cellulose, resulting in low nonspecific binding and making them ideal for use with complex biological samples. The beads also have excellent magnetic properties for rapid and efficient capture using a variety of magnetic stands. The affinity of biotin for streptavidin (Kd = 10[-15]) is one of the strongest and most stable interactions in biology; hence, the biotin-streptavidin interaction cannot be reversed under non-denaturing conditions. Therefore, we do not recommend the use of beads for applications in which the biotinylated molecules need to be recovered from the beads. High Capacity Magne Streptavidin Beads are well suited for pharmacokinetics studies of therapeutic antibodies during preclinical studies.