Life Science > Microbiology > Molecular Biology Reagents and Kits > DNA Reagents

FTO RNA Demethylase - 20 µg

Supplied by New England Biolabs

  • M0616S | FTO RNA Demethylase 20 g
  • M0616S | FTO RNA Demethylase 20 g
Average lead time: Call for Lead Time
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Product Description
Specifications
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Product Description
FTO RNA Demethylase is named the fat mass and obesity-associated protein (FTO) due to its association with human obesity. This enzyme is a homolog of the Fe(II)/ alpha-ketoglutarate – dependent AlkB dioxygenases and is an N6-methyladenosine (m6A) demethylase of eukaryotic mRNA. In vivo, FTO demethylates internal m6A and cap N6, 2 prime-O-dimethyladenosine (m6Am) in mRNA and snRNA. FTO also mediates N1-methyladenosine (m1A) demethylation in tRNA. In vitro, FTO demethylates m6A, m6Am and m3U in ssRNA, as well as N6-methyl-deoxyadenosine (6mA) and 3-methylthymine (3mT) on ssDNA.
Specifications
Inventory Number:
NEBM0616SEA
Part Number:
M0616S
Supplier:
New England Biolabs
Supplier's Lead Time:
Call for Lead Time
Quantity:
1 per EA
Contract Availability:
GSA
Country of Origin:
United States
Additional Information

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