Life Science > Proteomics > Protein Chemistry Reagents and Kits > Cell Lysis and Protein Extraction

Endonuclease VIII - 1000 units

by New England Biolabs

  • M0299S | Endonuclease VIII 1000 units
  • M0299S | Endonuclease VIII 1000 units
Average lead time: 5 to 7 Days
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Product Description
Specifications
Additional Information
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Product Description

Endonuclease VIII from E. coli acts as both an N-glycosylase and an AP-lyase. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site). The AP-lyase activity cleaves 3' and 5' to the AP site leaving a 5' phosphate and a 3' phosphate. Damaged bases recognized and removed by Endonuclease VIII include urea, 5, 6- dihydroxythymine, thymine glycol, 5-hydroxy-5- methylhydantoin, uracil glycol, 6-hydroxy-5, 6-dihydrothymine and methyltartronylurea. While Endonuclease VIII is similar to Endonuclease III, Endonuclease VIII has and lyase activity while Endonuclease III has only lyase activity.
Specifications
Inventory Number:
NEBM0299SEA
Part Number:
M0299S
Supplier:
New England Biolabs
Supplier's Lead Time:
5 to 7 Days
Quantity:
1000 per EA
Contract Availability:
GSA
Country of Origin:
United States
Additional Information

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