NEBNext® Enzymatic Methyl-seq v2 Conversion Module - 96 reactions

NEBNext Enzymatic Methyl-seq (EM-seq) is a high-performance enzyme-based alternative to bisulfite conversion for the identification of 5mC and 5hmC. Unlike bisulfite conversion, this highly efficient method minimizes DNA damage, resulting in superior detection of methylated cytosines, with fewer sequencing reads The new NEBNext Enzymatic Methyl-seq v2 Conversion Module has a wider input range (as low as 100 pg) than the original EM-seq Conversion Module. For use in Illumina sequencing workflows, we recommend use of the NEBNext Enzymatic Methyl-seq v2 Kit instead of this module. The full kit includes the EM-seq Adaptor, which has been optimized for high performance in the EM-seq workflow, as well as the high-efficiency NEBNext Ultra II library prep reagents, and these components are not included in the Conversion Module.