Chromatography > Chromatography Equipment > Chromatographs > Liquid Chromatographs (LC)

NanoAssemblr™ Ignite and Ignite+ nanoparticle formulation systems

Supplied by Cytiva

$134,900.00/EA

Average lead time: Call for Lead Time

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Product Description

Specifications

Additional Information

Product Description

NanoAssemblr™ Ignite™ instrument

Specifications

Inventory Number:

GEHNIN0001EA

Part Number:

NIN0001

Supplier:

Cytiva

Supplier's Lead Time:

Call for Lead Time

Quantity:

1 per EA

Contract Availability:

Country of Origin:

Canada

Features and Benefits 1::

Accelerated timelines – Simplified workflows and comprehensive technical support expedite drug development and data generation

Features and Benefits 2::

Reproducible – Automated and advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogenous particles

Features and Benefits 3::

Easy to use – Simple workflows and intuitive software allow users to be up and running quickly

Features and Benefits 4::

Minimized risk – The robust design of the system greatly reduces the chances of contamination and user errors, minimizing troubleshooting and downtime

Features and Benefits 5::

Controlled assembly – Precise control over fluid flow rates and ratios allows fine-tuning of the critical quality attributes (CQAs), including particle size, to your specifications

Features and Benefits 6::

Scalable – The system enables modeling of clinically relevant parameters and processes at small volumes to predictably scale optimized formulations on the NanoAssemblr™ Blaze system and NanoAssemblr™ commercial formulation system

Overview:

The NanoAssemblr™ Ignite and Ignite+ systems enable scalable, reproducible, and easy-to-use formulation of lipid nanoparticles (LNPs) for preclinical genomic medicine development.

Overview 2:

The NanoAssemblr™ Ignite system formulates at the bench scale with volumes of up to 20 mL and flow rates of up to 20 mL/min.

Overview 3:

The NanoAssemblr™ Ignite+ system builds on these features with expanded capabilities, formulating up to 60 mL at up to 200 mL/min. This flexibility supports small-scale de-risking of large-scale systems and initiates process development activities using simple, low-volume workflows.

Overview 4:

Scalable NxGen™ technology NanoAssemblr™ Ignite and NanoAssemblr™ Ignite+ systems feature NxGen™ technology, an advanced mixing architecture that uses toroidal structures within the flow path to maintain steady, consistent mixing conditions. This enables effective transfer of critical process parameters (CPPs) during scaling up while maintaining reproducibility and control.

Overview 5:

All cartridges are validated for single use only. Beginning in September 2025, customers can request a software upgrade that allows optional reuse of current NxGen™ and NxGen™ 500 cartridges. For advanced applications, the new NxGen™ scale-ready cartridge (coming soon) is a gamma-irradiated version of the NxGen™ 500 cartridge, designed with GMP in mind and optimized to minimize risks in early-phase and small-scale clinical trials.

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NanoAssemblr™ Ignite and Ignite+ nanoparticle formulation systems

Supplied by Cytiva

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