HiScreen Capto Core 700
High capacity and productivity in flowthrough mode.
Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
Wide operational window of pH and conductivity.
HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules.
Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligandactivated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.