Capto L antibody fragment purification resin, 200 mL
Suitable for the capture of a wide range of antibody fragments such as Fabs, dAbs, and singlechain fragment variable (scFv) .
High binding capacity, low ligand leakage, and selectivity for a broad range of antibody fragments reduces process time and amount of resin.
Enables a platform approach to antibody fragment purification.
Excellent productivity, process economy, and process design flexibility due to rigid matrix.
Hydrophilic base matrix ensures low levels of nonspecific binding and low levels of host cellderived impurities in the elution pool.
Fulfills industrial demands for security of supply, robust performance, and regulatory support.
The high binding capacity and selectivity for a broad range of antibody fragments makes Capto L an excellent capture platform for antibody fragments containing kappa light chains. Using Capto L requires minimal optimization and it produces high purity in one separation step. This results in significant savings in costs, effort, and time during process development. In addition, Capto L provides several advantages in manufacturing processes because the high selectivity of affinity capture reduces the number of subsequent polishing steps.
Capto L is available in prefilled PreDictor 96well plates, PreDictor RoboColumn™, as well as HiTrap and HiScreen prepacked columns for efficient highthroughput process development or smallscale purification