Capto adhere multimodal chromatography resin, 25 mL
Wide operational window of pH and conductivity.
Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
Twostep chromatographic process with protein A affinity, saves time and cuts operating costs.
Removes contaminants to formulation levels.
High capacity and productivity in flowthrough mode.
Capto adhere is a multimodal BioProcess medium designed for postprotein A purification of monoclonal antibodies (MAbs) at process scale. It is composed of a rigid, highflow agarose matrix and a novel multimodal ligand. The strong multimodal ligand gives a different selectivity compared to traditional ion exchangers. Capto adhere can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. Together with a Protein A capture step, like MabSelect SuRe, Capto adhere allows the design of a twostep chromatographic process for Mabs.
For optimal performance of Capto adhere, screening/optimization of loading conditions is recommended, preferably using modern highthroughput process development tools, such as PreDictor 96well filter plates.
Capto adhere is available in a range of different bulk pack sizes and convenient prepacked formats for easy scaleup and process development.
As member of the BioProcess media range, Capto adhere meets industrial demands with security of supply and comprehensive technical and regulatory support.