SP Sepharose XL, 300 mL
High loading capacities give more productive capture from clarified feedstocks.
Strong cation exchanger designed for capture steps
High chemical stability for effective CIP/sanitization
The hydrophilic nature of the base matrix ensures low levels of nonspecific binding leading to low levels of host cellderived impurities in the elution pool.
SP Sepharose XL is based on a highly crosslinked, bead formed 6% agarose matrix similar to the well established SP Sepharose Fast Flow media. Dextran chains are covalently coupled to the agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates
With its high loading capacities and excellent physical and chemical stability, SP Sepharose XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.
As member of the BioProcess media range, SP Sepharose XL meets industrial demands with security of supply and comprehensive technical and regulatory support.